| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Lee Gary K. | Chief Scientific Officer | C/O LYELL IMMUNOPHARMA, INC., 201 HASKINS WAY, SOUTH SAN FRANCISCO | /s/ Mark Meltz, Attorney-in-Fact | 12 Feb 2026 | 0001907345 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | LYEL | Common Stock | Sale | $39,085 | -1,671 | -9% | $23.39 | 16,938 | 11 Feb 2026 | Direct | F1, F2 |
| Id | Content |
|---|---|
| F1 | Shares automatically sold to cover tax withholding obligation from settlement of performance-based vested restricted stock units. |
| F2 | The price reported above reflects the weighted average price of the shares sold. The sale price ranged from $23.3939 to $24.6305 per share. Upon request from the SEC staff, the Issuer, or a security holder of the Issuer, the Reporting Person will provide full information regarding the number of shares sold at each separate price within the range set forth in this Form 4. |