Sandra Boenisch - 20 Aug 2025 Form 4 Insider Report for ANAVEX LIFE SCIENCES CORP. (AVXL)

Role: PFO & Treasurer
Signature: /s/ Sandra Boenisch
Issuer symbol: AVXL
Transactions as of: 20 Aug 2025
Net transactions value: $0
Form type: 4
Filing time: 22 Aug 2025, 17:30:21 UTC
Previous filing: 30 Apr 2025
Next filing: 03 Oct 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Boenisch Sandra	PFO & Treasurer	630 5TH AVENUE, 20TH FLOOR, NEW YORK	/s/ Sandra Boenisch	22 Aug 2025	0001655366

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	AVXL	Stock Option (Right to Buy)	Award	$0	+12,500		$0.000000	12,500	20 Aug 2025	Common Stock	12,500	$8.58	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	On March 31, 2025, the reporting person was granted an option to purchase 50,000 shares of common stock. The option vests in four equal tranches based on four performance milestones, one of which was Publication of preclinical blarcamesine prevention AD data. The performance criteria for this milestone was met, resulting in vesting of the option as to 12,500 shares.