Ryan J. Watts - Sep 3, 2025 Form 4 Insider Report for Denali Therapeutics Inc. (DNLI)

Role
President and CEO, Director
Signature
/s/ Tyler Nielsen, by power of attorney
Stock symbol
DNLI
Transactions as of
Sep 3, 2025
Transactions value $
$0
Form type
4
Date filed
9/5/2025, 04:43 PM
Previous filing
Jul 11, 2025
SEC
View on sec.gov

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
Watts Ryan J. President and CEO, Director C/O DENALI THERAPEUTICS INC., 161 OYSTER POINT BLVD., SOUTH SAN FRANCISCO /s/ Tyler Nielsen, by power of attorney 2025-09-05 0001724310

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction DNLI Common Stock Gift $0 -50K -2.27% $0.00 2.15M Sep 3, 2025 See footnote F1, F2
holding DNLI Common Stock 253K Sep 3, 2025 Direct F3
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id Content
F1 Reflects an in-kind charitable contribution of 50,000 shares of DNLI to a donor advised fund.
F2 The shares are held of record by the Watts Family 2015 Trust dated July 7, 2015, for which the Reporting Person serves as trustee.
F3 Includes 177,940 Unvested RSUs.