Derek J. Maetzold - 11 Mar 2026 Form 4 Insider Report for CASTLE BIOSCIENCES INC (CSTL)

Signature
/s/ Frank Stokes, Attorney-in-fact
Issuer symbol
CSTL
Transactions as of
11 Mar 2026
Net transactions value
-$1,132,821
Form type
4
Filing time
13 Mar 2026, 16:10:14 UTC
Previous filing
05 Mar 2026
Next filing
17 Mar 2026

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
MAETZOLD DEREK J Pres. & Chief Exec. Officer, Director C/O CASTLE BIOSCIENCES, INC., 1500 W. PARKWOOD AVE SUITE 400, FRIENDSWOOD /s/ Frank Stokes, Attorney-in-fact 13 Mar 2026 0001239501

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction CSTL Common Stock Options Exercise +6,226 +5.9% $2.39* 112,047 11 Mar 2026 Direct F1
transaction CSTL Common Stock Sale $451,947 -17,310 -15% $26.11 94,737 11 Mar 2026 Direct F1, F2
transaction CSTL Common Stock Sale $35,430 -1,357 -2.6% $26.11 51,566 11 Mar 2026 By The Maetzold Descendants 2020 Trust F1, F2, F3
transaction CSTL Common Stock Sale $30,286 -1,160 -2.6% $26.11 43,826 11 Mar 2026 By Derek Maetzold 2020 Irrevocable Trust F1, F2, F4
transaction CSTL Common Stock Sale $7,363 -282 -7.8% $26.11 3,336 11 Mar 2026 By The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk F1, F2, F5
transaction CSTL Common Stock Sale $7,284 -279 -7.7% $26.11 3,336 11 Mar 2026 By The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold F1, F2, F6
transaction CSTL Common Stock Sale $7,284 -279 -7.7% $26.11 3,336 11 Mar 2026 By The Maetzold 2018 Remainder Trust FBO John Derek Maetzold F1, F2, F7
transaction CSTL Common Stock Sale $7,284 -279 -7.7% $26.11 3,336 11 Mar 2026 By The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold F1, F2, F8
transaction CSTL Common Stock Sale $585,942 -23,179 -24% $25.28 71,558 12 Mar 2026 Direct F1, F9
holding CSTL Common Stock 85,959 11 Mar 2026 By DJM Grantor Retained Annuity Trust No. 5 F10
holding CSTL Common Stock 18,718 11 Mar 2026 By DJM Grantor Retained Annuity Trust No. 6 F11
holding CSTL Common Stock 44,323 11 Mar 2026 By DJM Grantor Retained Annuity Trust No. 7 F12

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction CSTL Stock option (right to buy) Options Exercise -6,226 -30% $0.000000* 14,282 11 Mar 2026 Common Stock 6,226 $2.39 Direct F1, F13
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.

Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).

Explanation of Responses:

Id Content
F1 These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 3, 2025.
F2 This transaction was executed in multiple trades at prices ranging from $25.800 to $26.630, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
F3 Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries.
F4 Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries.
F5 Held by The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk of which the Reporting Person is the trustee and his child is the beneficiary.
F6 Held by The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
F7 Held by The Maetzold 2018 Remainder Trust FBO John Derek Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
F8 Held by The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
F9 This transaction was executed in multiple trades at prices ranging from $24.900 to $25.705, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
F10 Held by DJM Grantor Retained Annuity Trust No. 5 of which the Reporting Person is the trustee and beneficiary.
F11 Held by DJM Grantor Retained Annuity Trust No. 6 of which the Reporting Person is the trustee and the beneficiaries are The Maetzold 2018 Remainder Trust FBO John Derek Maetzold, The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk, The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold and The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold.
F12 Held by DJM Grantor Retained Annuity Trust No. 7 of which the Reporting Person is the trustee and beneficiary.
F13 The shares subject to the option are fully vested.