| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Oelschlager Kristen M | Chief Operating Officer | C/O CASTLE BIOSCIENCES, INC., 505 S FRIENDSWOOD DRIVE, SUITE 401, FRIENDSWOOD | /s/ Frank Stokes, Attorney-in-fact | 19 Dec 2025 | 0001856565 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | CSTL | Common Stock | Sale | $585,292 | -14,888 | -55% | $39.31 | 12,323 | 17 Dec 2025 | Direct | F1 |
| holding | CSTL | Common Stock | 97,251 | 17 Dec 2025 | The Fritz Shorter Trust | F2 |
| Id | Content |
|---|---|
| F1 | This transaction was executed in multiple trades at prices ranging from $39.055 to 39.830, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |
| F2 | Held by the Fritz Shorter Trust of which the Reporting Person and her spouse are the trustees and beneficiaries. |