| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Juvenal Tobin W | Chief Commercial Officer | C/O CASTLE BIOSCIENCES, INC., 505 S FRIENDSWOOD DRIVE, SUITE 401, FRIENDSWOOD | /s/ Frank Stokes, Attorney-in-fact | 15 Dec 2025 | 0001856542 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | CSTL | Common Stock | Sale | $494,736 | -13,200 | -13% | $37.48 | 86,825 | 11 Dec 2025 | Direct | F1 |
| Id | Content |
|---|---|
| F1 | This transaction was executed in multiple trades at prices ranging from $37.31 to $37.72, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. |