| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Stokes Frank | Chief Financial Officer | C/O CASTLE BIOSCIENCES, INC., 505 S. FRIENDSWOOD DRIVE, SUITE 401, FRIENDSWOOD | /s/ Frank Stokes, Attorney-in-fact | 15 Dec 2025 | 0001782815 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | CSTL | Common Stock | Sale | $168,375 | -4,496 | -8.2% | $37.45 | 50,326 | 11 Dec 2025 | Direct |