DEREK J. MAETZOLD - 09 Dec 2025 Form 4 Insider Report for CASTLE BIOSCIENCES INC (CSTL)

Signature
/s/ Frank Stokes, Attorney-in-fact
Issuer symbol
CSTL
Transactions as of
09 Dec 2025
Transactions value $
-$734,955
Form type
4
Filing time
11 Dec 2025, 18:48:55 UTC
Previous filing
08 Dec 2025
Next filing
17 Dec 2025

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
MAETZOLD DEREK J Pres. & Chief Exec. Officer, Director C/O CASTLE BIOSCIENCES, INC., 505 S. FRIENDSWOOD DRIVE, SUITE 401, FRIENDSWOOD /s/ Frank Stokes, Attorney-in-fact 11 Dec 2025 0001239501

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction CSTL Common Stock Options Exercise +33.5K +89.21% 71K 09 Dec 2025 Direct F1
transaction CSTL Common Stock Tax liability -$504K -13.2K -18.55% $38.25 57.9K 09 Dec 2025 Direct
transaction CSTL Common Stock Options Exercise +15.4K +26.66% 73.3K 10 Dec 2025 Direct F1
transaction CSTL Common Stock Tax liability -$231K -6.07K -8.28% $38.02 67.2K 10 Dec 2025 Direct
holding CSTL Common Stock 52.9K 09 Dec 2025 By The Maetzold Descendants 2020 Trust F2
holding CSTL Common Stock 45K 09 Dec 2025 By Derek Maetzold 2020 Irrevocable Trust F3
holding CSTL Common Stock 3.62K 09 Dec 2025 By The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk F4
holding CSTL Common Stock 3.62K 09 Dec 2025 By The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold F5
holding CSTL Common Stock 3.62K 09 Dec 2025 By The Maetzold 2018 Remainder Trust FBO John Derek Maetzold F6
holding CSTL Common Stock 3.62K 09 Dec 2025 By The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold F7
holding CSTL Common Stock 86K 09 Dec 2025 By DJM Grantor Retained Annuity Trust No. 5 F8
holding CSTL Common Stock 18.7K 09 Dec 2025 By DJM Grantor Retained Annuity Trust No. 6 F9
holding CSTL Common Stock 44.3K 09 Dec 2025 By DJM Grantor Retained Annuity Trust No. 7 F10

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction CSTL Restricted Stock Units Options Exercise $0 -33.5K -50% $0.00 33.5K 09 Dec 2025 Common Stock 33.5K Direct F1, F11
transaction CSTL Restricted Stock Units Options Exercise $0 -15.4K -100% $0.00 0 10 Dec 2025 Common Stock 15.4K Direct F1, F12
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id Content
F1 Each Restricted Stock Unit ("RSU") represents the right to receive one share of the Issuer's Common Stock.
F2 Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries.
F3 Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries.
F4 Held by The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk of which the Reporting Person is the trustee and his child is the beneficiary.
F5 Held by The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
F6 Held by The Maetzold 2018 Remainder Trust FBO John Derek Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
F7 Held by The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
F8 Held by DJM Grantor Retained Annuity Trust No. 5 of which the Reporting Person is the trustee and beneficiary.
F9 Held by DJM Grantor Retained Annuity Trust No. 6 of which the Reporting Person is the trustee and the beneficiaries are The Maetzold 2018 Remainder Trust FBO John Derek Maetzold, The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk, The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold and The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold.
F10 Held by DJM Grantor Retained Annuity Trust No. 7 of which the Reporting Person is the trustee and beneficiary.
F11 On December 9, 2022, the Reporting Person was granted 133,983 RSUs which vest in four equal installments beginning on December 9, 2023.
F12 On December 10, 2021, the Reporting Person was granted 61,698 RSUs which vest in four equal installments beginning on December 10, 2022.