| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| MAETZOLD DEREK J | Pres. & Chief Exec. Officer, Director | C/O CASTLE BIOSCIENCES, INC., 505 S. FRIENDSWOOD DRIVE, SUITE 401, FRIENDSWOOD | /s/ Frank Stokes, Attorney-in-fact | 11 Dec 2025 | 0001239501 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | CSTL | Common Stock | Options Exercise | +33.5K | +89.21% | 71K | 09 Dec 2025 | Direct | F1 | ||
| transaction | CSTL | Common Stock | Tax liability | -$504K | -13.2K | -18.55% | $38.25 | 57.9K | 09 Dec 2025 | Direct | |
| transaction | CSTL | Common Stock | Options Exercise | +15.4K | +26.66% | 73.3K | 10 Dec 2025 | Direct | F1 | ||
| transaction | CSTL | Common Stock | Tax liability | -$231K | -6.07K | -8.28% | $38.02 | 67.2K | 10 Dec 2025 | Direct | |
| holding | CSTL | Common Stock | 52.9K | 09 Dec 2025 | By The Maetzold Descendants 2020 Trust | F2 | |||||
| holding | CSTL | Common Stock | 45K | 09 Dec 2025 | By Derek Maetzold 2020 Irrevocable Trust | F3 | |||||
| holding | CSTL | Common Stock | 3.62K | 09 Dec 2025 | By The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk | F4 | |||||
| holding | CSTL | Common Stock | 3.62K | 09 Dec 2025 | By The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold | F5 | |||||
| holding | CSTL | Common Stock | 3.62K | 09 Dec 2025 | By The Maetzold 2018 Remainder Trust FBO John Derek Maetzold | F6 | |||||
| holding | CSTL | Common Stock | 3.62K | 09 Dec 2025 | By The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold | F7 | |||||
| holding | CSTL | Common Stock | 86K | 09 Dec 2025 | By DJM Grantor Retained Annuity Trust No. 5 | F8 | |||||
| holding | CSTL | Common Stock | 18.7K | 09 Dec 2025 | By DJM Grantor Retained Annuity Trust No. 6 | F9 | |||||
| holding | CSTL | Common Stock | 44.3K | 09 Dec 2025 | By DJM Grantor Retained Annuity Trust No. 7 | F10 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | CSTL | Restricted Stock Units | Options Exercise | $0 | -33.5K | -50% | $0.00 | 33.5K | 09 Dec 2025 | Common Stock | 33.5K | Direct | F1, F11 | |
| transaction | CSTL | Restricted Stock Units | Options Exercise | $0 | -15.4K | -100% | $0.00 | 0 | 10 Dec 2025 | Common Stock | 15.4K | Direct | F1, F12 |
| Id | Content |
|---|---|
| F1 | Each Restricted Stock Unit ("RSU") represents the right to receive one share of the Issuer's Common Stock. |
| F2 | Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries. |
| F3 | Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries. |
| F4 | Held by The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk of which the Reporting Person is the trustee and his child is the beneficiary. |
| F5 | Held by The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold of which the Reporting Person is the trustee and his child is the beneficiary. |
| F6 | Held by The Maetzold 2018 Remainder Trust FBO John Derek Maetzold of which the Reporting Person is the trustee and his child is the beneficiary. |
| F7 | Held by The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold of which the Reporting Person is the trustee and his child is the beneficiary. |
| F8 | Held by DJM Grantor Retained Annuity Trust No. 5 of which the Reporting Person is the trustee and beneficiary. |
| F9 | Held by DJM Grantor Retained Annuity Trust No. 6 of which the Reporting Person is the trustee and the beneficiaries are The Maetzold 2018 Remainder Trust FBO John Derek Maetzold, The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk, The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold and The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold. |
| F10 | Held by DJM Grantor Retained Annuity Trust No. 7 of which the Reporting Person is the trustee and beneficiary. |
| F11 | On December 9, 2022, the Reporting Person was granted 133,983 RSUs which vest in four equal installments beginning on December 9, 2023. |
| F12 | On December 10, 2021, the Reporting Person was granted 61,698 RSUs which vest in four equal installments beginning on December 10, 2022. |