Tobin W. Juvenal - Nov 20, 2025 Form 4 Insider Report for CASTLE BIOSCIENCES INC (CSTL)

Role
Chief Commercial Officer
Signature
/s/ Frank Stokes, Attorney-in-fact
Stock symbol
CSTL
Transactions as of
Nov 20, 2025
Transactions value $
-$151,115
Form type
4
Date filed
11/24/2025, 04:24 PM
Previous filing
Nov 14, 2025
SEC
View on sec.gov

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
Juvenal Tobin W Chief Commercial Officer C/O CASTLE BIOSCIENCES, INC., 505 S FRIENDSWOOD DRIVE, SUITE 401, FRIENDSWOOD /s/ Frank Stokes, Attorney-in-fact 2025-11-24 0001856542

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction CSTL Common Stock Options Exercise $15.9K +4.69K +5.55% $3.38 89.3K Nov 20, 2025 Direct F1, F2
transaction CSTL Common Stock Sale -$167K -4.69K -5.26% $35.58 84.6K Nov 20, 2025 Direct F1, F2, F3
holding CSTL Common Stock 2.23K Nov 20, 2025 By Tobin W and Susan M Juvenal Family Revocable Trust F4

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction CSTL Stock option (right to buy) Options Exercise $0 -4.69K -29.51% $0.00 11.2K Nov 20, 2025 Common Stock 4.69K $3.38 Direct F1, F5
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.

Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).

Explanation of Responses:

Id Content
F1 This transaction was made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on September 11, 2024.
F2 Reflects an adjustment of 68 shares to the number of shares beneficially owned following a reconciliation of the Reporting Person's records.
F3 This transaction was executed in multiple trades at prices ranging from $35.40 to $35.85, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
F4 Held by Tobin W and Susan M Juvenal Family Revocable Trust of which the Reporting Person and his spouse are the trustees and the Reporting Person, his spouse and their children are the beneficiaries.
F5 The shares subject to the option are fully vested.