| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Madsen Julia | Sr. VP and GM, Life Sciences | 70 SIR JOHN ROGERSON'S QUAY, DUBLIN 2, IRELAND | /s/ John P. Ubbing, Authorized Representative under Power of Attorney | 03 Oct 2025 | 0001819129 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | STE | Ordinary Shares | Tax liability | $0 | -52 | -0.48% | $0.000000 | 10,710 | 01 Oct 2025 | Direct | F1, F2 |
| Id | Content |
|---|---|
| F1 | 52 shares were withheld from the 144 restricted shares that vested on October 1, 2025. These 52 shares represent the value of the taxes required to be withheld pursuant to applicable employment or tax laws, as determined by the Issuer. These 144 ordinary shares were awarded to Ms. Madsen on October 1, 2021. These vested shares were valued at the NYSE closing market price on October 1, 2025. |
| F2 | As of October 1, 2025, 4,003 of these ordinary shares are restricted. The restrictions on these ordinary shares lapse as follows: 578 on June 1, 2026, 352 on June 2, 2026; 666 on June 3, 2026; 542 on June 4, 2026; 666 on June 3, 2027; 542 on June 4, 2027 and 666 on June 5, 2028. |