Peter A. Thompson - Jan 3, 2022 Form 4 Insider Report for ALPINE IMMUNE SCIENCES, INC. (ALPN)

Role: Director, 10%+ Owner
Signature: /s/ James Paul Rickey, attorney-in-fact
Stock symbol: ALPN
Transactions as of: Jan 3, 2022
Transactions value $: $0
Form type: 4
Date filed: 1/4/2022, 04:19 PM
Previous filing: Dec 30, 2021
Next filing: May 20, 2022
SEC: View on sec.gov

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	ALPN	Stock Option (Right to buy)	Award	$0	+10K		$0.00	10K	Jan 3, 2022	Common Stock	10K	$13.89	Direct	F1, F2, F3

Showing 1 to 1 of 1 entries

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The exercise price is equal to the closing price per share of Common Stock as reported on the Nasdaq Global Market on the date of grant.
F2	1/12th of the shares subject to the option become vested and exercisable on February 3, 2022 and 1/12th of the shares subject to the option shall vest monthly thereafter.
F3	The Reporting Person is a member of OrbiMed Advisors LLC ("OrbiMed Advisors"). Pursuant to an agreement with OrbiMed Advisors, the Reporting Person is obligated to transfer these securities, or the economic benefit thereof, to OrbiMed Advisors and OrbiMed Capital GP VI LLC, which will in turn ensure that such securities or economic benefits are provided to OrbiMed Private Investments VI, LP.