Manmeet Singh Soni - 21 Oct 2025 Form 4 Insider Report for Summit Therapeutics Inc. (SMMT)

Role: COO and CFO, Director
Signature: /s/ Manmeet Soni
Issuer symbol: SMMT
Transactions as of: 21 Oct 2025
Net transactions value: +$999,985
Form type: 4
Filing time: 23 Oct 2025, 16:10:15 UTC
Previous filing: 19 Aug 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Soni Manmeet Singh	COO and CFO, Director	C/O SUMMIT THERAPEUTICS INC., 601 BRICKELL KEY DRIVE, SUITE 1000, MIAMI	/s/ Manmeet Soni	23 Oct 2025	0001569769

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	SMMT	Common Stock	Award	$999,985	+53,361	+1.8%	$18.74	3,073,603	21 Oct 2025	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Acquired in a private placement transaction pursuant to the terms of a definitive agreement, dated as of October 21, 2025, pursuant to which the Issuer agreed to sell shares of common stock to the Reporting Person and certain other parties at a purchase price of $18.74 per share. The transaction is anticipated to close on or about October 23, 2025.