Tran Nguyen - Jan 18, 2023 Form 4 Insider Report for PROTHENA CORP PUBLIC LTD CO (PRTA)

Role: Chief Strategy Officer and CFO
Signature: /s/ Michael Malecek, as Attorney in Fact for Tran B. Nguyen
Stock symbol: PRTA
Transactions as of: Jan 18, 2023
Transactions value $: -$488,006
Form type: 4
Date filed: 1/20/2023, 08:30 PM
Previous filing: Dec 23, 2022
Next filing: Feb 17, 2023

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	PRTA	Ordinary Shares, par value $0.01 per share	Options Exercise	$67.3K	+10K	+312.5%	$6.73^*	13.2K	Jan 18, 2023	Direct
transaction	PRTA	Ordinary Shares, par value $0.01 per share	Sale	-$402K	-7.28K	-55.13%	$55.18	5.92K	Jan 18, 2023	Direct	F1, F2
transaction	PRTA	Ordinary Shares, par value $0.01 per share	Sale	-$117K	-2.09K	-35.2%	$56.32	3.84K	Jan 18, 2023	Direct	F1, F3
transaction	PRTA	Ordinary Shares, par value $0.01 per share	Sale	-$36.3K	-638	-16.62%	$56.97	3.2K	Jan 18, 2023	Direct	F1, F4

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	PRTA	Stock Option (Right to Buy)	Options Exercise	$0	-10K	-33.33%	$0.00	20K	Jan 18, 2023	Ordinary Shares	10K	$6.73	Direct	F5, F6

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person in connection with a court stipulation and proposed order regarding the separation of assets ("Court Order") in anticipation of a potential divorce settlement agreement.
F2	The transaction was executed in multiple trades in prices ranging from $54.77 to $55.755, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in footnotes 2 through 4 of this Form 4.
F3	The transaction was executed in multiple trades in prices ranging from $55.78 to $56.755, inclusive.
F4	The transaction was executed in multiple trades in prices ranging from $56.815 to $57.355, inclusive.
F5	The option was granted on April 1, 2013 and all shares subject to the option were fully vested and exercisable. The option will expire in approximately two months and be forfeited to the extent it is not exercised on or prior to March 31, 2023.
F6	The Reporting Person holds options that give him the right to acquire an aggregate of 873,837 shares at exercise prices ranging from $6.73 to $32.45, of which 708,753 are currently exercisable, and 165,084 are currently unexercisable but vest over time, subject to the Reporting Person's continued employment with the Issuer on each applicable vesting date of each option award. Certain of these options are subject to the Court Order.