Shane Cooke - Nov 10, 2022 Form 4 Insider Report for PROTHENA CORP PUBLIC LTD CO (PRTA)

Role: Director
Signature: /s/ Michael Malecek, as Attorney in Fact for Shane M. Cooke
Stock symbol: PRTA
Transactions as of: Nov 10, 2022
Transactions value $: -$248,778
Form type: 4
Date filed: 11/10/2022, 08:30 PM
Previous filing: Oct 12, 2022
Next filing: Dec 12, 2022

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	PRTA	Ordinary Shares, par value $0.01 per share	Options Exercise	$32.1K	+5K		$6.41^*	5K	Nov 10, 2022	Direct
transaction	PRTA	Ordinary Shares, par value $0.01 per share	Sale	-$13.8K	-255	-5.1%	$54.20	4.75K	Nov 10, 2022	Direct	F1, F2
transaction	PRTA	Ordinary Shares, par value $0.01 per share	Sale	-$217K	-3.87K	-81.56%	$56.14	875	Nov 10, 2022	Direct	F1, F3
transaction	PRTA	Ordinary Shares, par value $0.01 per share	Sale	-$49.7K	-875	-100%	$56.85	0	Nov 10, 2022	Direct	F1, F4

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	PRTA	Stock Option (Right to Buy)	Options Exercise	$0	-5K	-33.33%	$0.00	10K	Nov 10, 2022	Ordinary Shares	5K	$6.41	Direct	F5

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.
F2	The transaction was executed in multiple trades in prices ranging from $54.005 to $55.00, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the ranges set forth in footnotes 2 through 4 of this Form 4.
F3	The transaction was executed in multiple trades in prices ranging from $55.51 to $56.50, inclusive.
F4	The transaction was executed in multiple trades in prices ranging from $56.52 to $57.12, inclusive.
F5	The option was granted on January 29, 2013, and all shares subject to the option were fully vested and exercisable January 29, 2014. The option will expire in approximately three months and be forfeited to the extent it is not exercised on or prior to January 29, 2023.