Phillip Frost - Nov 26, 2025 Form 4 Insider Report for Cocrystal Pharma, Inc. (COCP)

Role
Director, 10%+ Owner
Signature
/s/ Phillip Frost, MD ET AL
Stock symbol
COCP
Transactions as of
Nov 26, 2025
Transactions value $
$3,975
Form type
4
Date filed
11/28/2025, 09:00 AM
Previous filing
Nov 25, 2025
SEC
View on sec.gov

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
FROST PHILLIP MD ET AL Director, 10%+ Owner 4400 BISCAYNE BLVD, MIAMI /s/ Phillip Frost, MD ET AL 2025-11-28 0000898860

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction COCP Common Stock Purchase $1.5K +1.5K +0.09% $1.00 1.7M Nov 26, 2025 By Frost Gamma Investments Trust F1
transaction COCP Common Stock Purchase $2.48K +2.5K +0.15% $0.99 1.7M Nov 26, 2025 By Frost Gamma Investments Trust F1
holding COCP Common Stock 27.1K Nov 26, 2025 Direct F2
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id Content
F1 These shares are held by Frost Gamma Investments Trust, of which Phillip Frost M.D., is the trustee. Frost Gamma L.P. is the sole and exclusive beneficiary of Frost Gamma Investments Trust. Dr. Frost is one of two limited partners of Frost Gamma L.P. The general partner of Frost Gamma L.P. is Frost Gamma, Inc., and the sole stockholder of Frost Gamma, Inc. is Frost-Nevada Corporation. Dr. Frost is the sole stockholder of Frost-Nevada Corporation. The Reporting Person disclaims beneficial ownership of the securities held by Frost Gamma Investments Trust except to the extent of any pecuniary interest therein, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of these securities for purposes of Section 16 or for any other purpose.
F2 Includes shares of common stock issuable upon vesting of restricted stock units.

Remarks:

This Form 4 does not include any of the securities owned directly by OPKO Health, Inc., a company of which Dr. Frost is the Chairman of the Board and Chief Executive Officer, concerning the securities of which Dr. Frost does not hold voting and investment control. Dr. Frost disclaims beneficial ownership of the securities held by OPKO Health, Inc. except to the extent of any pecuniary interest therein and this report shall not be deemed an admission that Dr. Frost is the beneficial owner of the securities for purposes of Section 16 or for any other purpose.