| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| RIOUX PATRICE | Acting Chief Medical Officer | 1000 SKOKIE BLVD SUITE 350, WILMETTE | /s/ Quan Vu, Attorney-in-fact | 05 Jan 2026 | 0001241033 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | MNPR | Stock Option | Award | $0 | +2,000 | $0.000000 | 2,000 | 01 Jan 2026 | Common Stock | 2,000 | $65.30 | Direct | F1 |
| Id | Content |
|---|---|
| F1 | Stock Options vesting commenced on January 1, 2026 as follows: 1/12th of the 2,000 options vest on January 31, 2026 and each subsequent month-end thereafter. |