| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Gruber James R. | Chief Financial Officer | C/O ETON PHARMACEUTICALS, INC., 21925 W. FIELD PARKWAY, SUITE 235, DEERPARK | /s/ James R. Gruber | 12 Dec 2025 | 0001923165 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | ETON | Common Stock | Tax liability | $77,169 | -4,542 | -2.1% | $16.99 | 215,713 | 12 Dec 2025 | Direct | F1, F2, F3 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | ETON | Restricted Stock Units | Award | $0 | +5,502 | +2.7% | $0.000000 | 210,255 | 11 Dec 2025 | Common Stock | 5,502 | Direct | F4, F5 |
| Id | Content |
|---|---|
| F1 | Shares withheld by the Issuer to satisfy applicable withholding taxes upon the vesting of restricted stock units. |
| F2 | The shares were sold in multiple trades at prices ranging from $16.94 to $17.07. The price reported above reflects the weighted average sales price. |
| F3 | The Reporting Person will provide upon request by the Securities and Exchange Commission staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased or sold at each separate price. |
| F4 | Each restricted stock unit represents a contingent right to receive one share of ETON Common Stock. |
| F5 | The restricted stock units vest immediately as of the award date. |