Andrew Cittadine - 02 Dec 2025 Form 4 Insider Report for Monopar Therapeutics (MNPR)

Role: Chief Operating Officer
Signature: /s/ Quan Vu, Attorney-in-fact
Issuer symbol: MNPR
Transactions as of: 02 Dec 2025
Net transactions value: $0
Form type: 4
Filing time: 08 Dec 2025, 16:50:48 UTC
Previous filing: 02 Oct 2025
Next filing: 05 Jan 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Cittadine Andrew	Chief Operating Officer	1000 SKOKIE BLVD SUITE 350, WILMETTE	/s/ Quan Vu, Attorney-in-fact	08 Dec 2025	0001863624

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	MNPR	Stock Options	Award	$0	+8,969		$0.000000	8,969	02 Dec 2025	Common Stock	8,969	$75.94	Direct	F1
transaction	MNPR	Restricted Stock Units	Award	$0	+13,919	+36%	$0.000000	52,593	02 Dec 2025	Common Stock	13,919	$0.000000	Direct	F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Options vest 6/48ths on June 30, 2026, and 1/48th per month thereafter.
F2	RSUs vest 6/48ths on June 30, 2026, and 3/48ths per quarter thereafter.