Tactic Pharma LLC - 24 Sep 2025 Form 4 Insider Report for Monopar Therapeutics (MNPR)

Role: 10%+ Owner
Signature: /s/ Chandler Robinson, Attorney-in-fact
Issuer symbol: MNPR
Transactions as of: 24 Sep 2025
Net transactions value: -$34,999,957
Form type: 4
Filing time: 26 Sep 2025, 15:53:30 UTC
Previous filing: 04 Apr 2025
SEC: View on sec.gov

Reporting Owners (5)

Name	Relationship	Address	Signature	Signature date	CIK
Tactic Pharma LLC	10%+ Owner	C/O 598 ROCKEFELLER RD, LAKE FOREST	/s/ Chandler Robinson, Attorney-in-fact	26 Sep 2025	0001727357
Robinson Chandler	Chief Executive Officer, Director	1000 SKOKIE BLVD SUITE 350, WILMETTE	/s/ Chandler Robinson, Attorney-in-fact	26 Sep 2025	0001727334
Brown Michael J	Member of 10% Owner Group	C/O 598 ROCKEFELLER RD, LAKE FOREST	/s/ Chandler Robinson, Attorney-in-fact	26 Sep 2025	0001035909
O'Halloran Thomas V.	Member of 10% Owner Group	C/O 598 ROCKEFELLER RD, LAKE FOREST	/s/ Chandler Robinson, Attorney-in-fact	26 Sep 2025	0001727481
Mazar Andrew Paul	Member of 10% Owner Group	C/O 598 ROCKEFELLER RD, LAKE FOREST	/s/ Chandler Robinson, Attorney-in-fact	26 Sep 2025	0001727393

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	MNPR	Common Stock	Sale	$34,999,957	-550,229	-67%	$63.61	272,026	24 Sep 2025	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Tactic Pharma LLC is no longer subject to Section 16 filing requirements. Form 4 or Form 5 obligations may continue.

Explanation of Responses:

Id	Content
F1	This Form 4 is being filed on behalf of Tactic Pharma LLC, an Illinois limited liability company ("Tactic"), and its managers, Andrew P. Mazar, Chandler D. Robinson, Michael J. Brown, and Thomas V. O'Halloran (collectively, the "Reporting Persons"). The managers collectively have voting control over the securities described herein. The managers each disclaim ownership of the shares of common stock owned by Tactic, except to the extent of their pecuniary interest therein. The Reporting Persons are no longer subject to Section 16, except for Chandler D. Robinson, who serves as Chief Executive Officer of Monopar Therapeutics Inc.

Content

This Form 4 is being filed on behalf of Tactic Pharma LLC, an Illinois limited liability company ("Tactic"), and its managers, Andrew P. Mazar, Chandler D. Robinson, Michael J. Brown, and Thomas V. O'Halloran (collectively, the "Reporting Persons"). The managers collectively have voting control over the securities described herein. The managers each disclaim ownership of the shares of common stock owned by Tactic, except to the extent of their pecuniary interest therein. The Reporting Persons are no longer subject to Section 16, except for Chandler D. Robinson, who serves as Chief Executive Officer of Monopar Therapeutics Inc.