Robert Charles Swanton - 12 Aug 2025 Form 3 Insider Report for BICYCLE THERAPEUTICS PLC (BCYC)

Role: Director
Signature: /s/ Travis Thompson, Attorney-in-Fact
Issuer symbol: BCYC
Transactions as of: 12 Aug 2025
Net transactions value: $0
Form type: 3
Filing time: 14 Aug 2025, 16:23:55 UTC
Next filing: 06 Oct 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Swanton Robert Charles	Director	C/O BICYCLE THERAPEUTICS PLC, BLOCKS A & B, PORTWAY BUILDING, CAMBRIDGE, UNITED KINGDOM	/s/ Travis Thompson, Attorney-in-Fact	14 Aug 2025	0002079922

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
holding	BCYC	Ordinary Shares						3,089	12 Aug 2025	Direct	F1

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
holding	BCYC	Stock Option (right to buy)							12 Aug 2025	Ordinary Shares	2,000	$18.85	Direct	F2
holding	BCYC	Stock Option (right to buy)							12 Aug 2025	Ordinary Shares	2,000	$24.58	Direct	F3

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	2,625 of the ordinary shares represent a restricted share unit ("RSU") award. The RSUs shall vest in 12 equal quarterly installments, with the first such installment vesting on October 2, 2025.
F2	Fully vested and exerciseable.
F3	This option vested with respect to one-fourth (1/4) of the total number of shares underlying the option on September 16, 2023 and the remaining shares vested or shall vest in 36 equal monthly installments thereafter.