| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| MCINERNEY TIMOTHY | Director | C/O SILENCE THERAPEUTICS PLC, 72 HAMMERSMITH ROAD, LONDON, UNITED KINGDOM | /s/ Rhonda Hellums, Attorney-in-Fact | 20 May 2025 | 0001226020 |
No securities are beneficially owned.