Vincent J. Angotti - 02 Apr 2025 Form 4 Insider Report for TALPHERA, INC. (TLPH)

Role: CHIEF EXECUTIVE OFFICER, Director
Signature: /s/ Martha Adler, Attorney-in-Fact
Issuer symbol: TLPH
Transactions as of: 02 Apr 2025
Net transactions value: +$125,000
Form type: 4
Filing time: 03 Apr 2025, 16:28:23 UTC
Previous filing: 18 Feb 2025
Next filing: 20 Feb 2026
SEC: View on sec.gov

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	TLPH	Common Stock	Purchase	$125,000	+213,310	+112%	$0.5860	403,769	02 Apr 2025	Direct
transaction	TLPH	Common Stock	Award	$0	+61,000	+15%	$0.000000	474,769	02 Apr 2025	Direct	F1, F2

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	TLPH	Stock Option (Right to Buy)	Award	$0	+365,000		$0.000000	365,000	02 Apr 2025	Common Stock	365,000	$0.5830	Direct	F3

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The restricted stock units shall vest in three equal consecutive annual installments on April 2, 2026, April 2, 2027 and April 2, 2028.
F2	Balance includes non-reportable acquisition of 10,000 shares of Common Stock through the Company's Employee Stock Purchase Plan.
F3	On April 2, 2025, the reporting person was granted an option to purchase 365,000 shares of common stock. One fourth (1/4th) of the option shares shall vest on the one year anniversary of the grant date, and the remaining balance of the option shares shall vest in 36 equal consecutive monthly installments thereafter until fully vested so long as the reporting person remains in continuous service through such applicable vesting periods.