| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Pauwels Eric | CHIEF BUSINESS OFFICER | C/O PTC THERAPEUTICS, INC., 500 WARREN CORPORATE CENTER DRIVE, WARREN | /s/ Avraham S. Adler, Attorney-in-Fact | 23 Dec 2025 | 0001323212 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | PTCT | Common Stock | Options Exercise | $9,176 | +138 | +0.2% | $66.49 | 70,511 | 19 Dec 2025 | Direct | F1 |
| transaction | PTCT | Common Stock | Sale | $2,799 | -37 | -0.05% | $75.66 | 70,474 | 19 Dec 2025 | Direct | F1, F2 |
| transaction | PTCT | Common Stock | Sale | $3,245 | -42 | -0.06% | $77.26 | 70,432 | 19 Dec 2025 | Direct | F1, F3 |
| transaction | PTCT | Common Stock | Sale | $4,603 | -59 | -0.08% | $78.01 | 70,373 | 19 Dec 2025 | Direct | F1, F4 |
| transaction | PTCT | Common Stock | Options Exercise | $10,176 | +565 | +0.8% | $18.01 | 70,938 | 19 Dec 2025 | Direct | F1 |
| transaction | PTCT | Common Stock | Sale | $14,562 | -193 | -0.27% | $75.45 | 70,745 | 19 Dec 2025 | Direct | F1, F5 |
| transaction | PTCT | Common Stock | Sale | $24,329 | -313 | -0.44% | $77.73 | 70,432 | 19 Dec 2025 | Direct | F1, F6 |
| transaction | PTCT | Common Stock | Sale | $4,627 | -59 | -0.08% | $78.43 | 70,373 | 19 Dec 2025 | Direct | F1, F7 |
| transaction | PTCT | Common Stock | Options Exercise | $1,316,834 | +19,805 | +28% | $66.49 | 90,178 | 19 Dec 2025 | Direct | F1 |
| transaction | PTCT | Common Stock | Sale | $113,655 | -1,500 | -1.7% | $75.77 | 88,678 | 19 Dec 2025 | Direct | F1, F8 |
| transaction | PTCT | Common Stock | Sale | $346,309 | -4,537 | -5.1% | $76.33 | 84,141 | 19 Dec 2025 | Direct | F1, F9 |
| transaction | PTCT | Common Stock | Sale | $817,997 | -10,548 | -13% | $77.55 | 73,593 | 19 Dec 2025 | Direct | F1, F10 |
| transaction | PTCT | Common Stock | Sale | $252,223 | -3,220 | -4.4% | $78.33 | 70,373 | 19 Dec 2025 | Direct | F1, F11 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | PTCT | Stock Option (Right to Buy) | Options Exercise | $0 | -138 | -0.69% | $0.000000 | 19,805 | 19 Dec 2025 | Common Stock | 138 | $66.49 | Direct | F1, F12 |
| transaction | PTCT | Stock Option (Right to Buy) | Options Exercise | $0 | -565 | -3.1% | $0.000000 | 17,566 | 19 Dec 2025 | Common Stock | 565 | $18.01 | Direct | F1, F12 |
| transaction | PTCT | Stock Option (Right to Buy) | Options Exercise | $0 | -19,805 | -100% | $0.000000 | 0 | 19 Dec 2025 | Common Stock | 19,805 | $66.49 | Direct | F1, F12 |
Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.
Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).
| Id | Content |
|---|---|
| F1 | This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025. |
| F2 | This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $75.20 to $76.08 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. |
| F3 | This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $76.60 to $77.55 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. |
| F4 | This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $77.65 to $78.52 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. |
| F5 | This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $75.04 to $75.91 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. |
| F6 | This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $77.25 to $78.22 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. |
| F7 | This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $78.34 to $78.49 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. |
| F8 | This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $75.05 to $76.01 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. |
| F9 | This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $76.05 to $76.77 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. |
| F10 | This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $77.10 to $78.02 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. |
| F11 | This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $78.13 to $78.56 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price. |
| F12 | Currently exercisable. |