Eric Pauwels - 17 Dec 2025 Form 4 Insider Report for PTC THERAPEUTICS, INC. (PTCT)

Signature
/s/ Avraham S. Adler, Attorney-in-Fact
Issuer symbol
PTCT
Transactions as of
17 Dec 2025
Net transactions value
-$578,261
Form type
4
Filing time
19 Dec 2025, 17:20:05 UTC
Previous filing
09 Sep 2025
Next filing
23 Dec 2025

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
Pauwels Eric CHIEF BUSINESS OFFICER C/O PTC THERAPEUTICS, INC., 500 WARREN CORPORATE CENTER DRIVE, WARREN /s/ Avraham S. Adler, Attorney-in-Fact 19 Dec 2025 0001323212

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction PTCT Common Stock Options Exercise $82,780 +1,245 +1.7% $66.49 74,157 17 Dec 2025 Direct F1
transaction PTCT Common Stock Sale $93,724 -1,245 -1.7% $75.28 72,912 17 Dec 2025 Direct F1, F2
transaction PTCT Common Stock Options Exercise $66,349 +3,684 +5.2% $18.01 74,157 17 Dec 2025 Direct F1
transaction PTCT Common Stock Sale $269,911 -3,584 -4.8% $75.31 70,473 17 Dec 2025 Direct F1, F3
transaction PTCT Common Stock Sale $7,600 -100 -0.14% $76.00 70,373 17 Dec 2025 Direct F1
transaction PTCT Common Stock Options Exercise $2,351,153 +35,361 +50% $66.49 105,734 17 Dec 2025 Direct F1
transaction PTCT Common Stock Sale $2,660,090 -35,261 -33% $75.44 70,473 17 Dec 2025 Direct F1, F4
transaction PTCT Common Stock Sale $7,600 -100 -0.14% $76.00 70,373 17 Dec 2025 Direct F1
transaction PTCT Common Stock Options Exercise $7,979 +120 +0.17% $66.49 70,493 18 Dec 2025 Direct F1
transaction PTCT Common Stock Sale $9,002 -120 -0.17% $75.02 70,373 18 Dec 2025 Direct F1, F5
transaction PTCT Common Stock Options Exercise $4,521 +251 +0.36% $18.01 70,624 18 Dec 2025 Direct F1
transaction PTCT Common Stock Sale $18,825 -251 -0.36% $75.00 70,373 18 Dec 2025 Direct F1
transaction PTCT Common Stock Options Exercise $188,233 +2,831 +4% $66.49 73,204 18 Dec 2025 Direct F1
transaction PTCT Common Stock Sale $212,523 -2,831 -3.9% $75.07 70,373 18 Dec 2025 Direct F1, F6

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction PTCT Stock Option (Right to Buy) Options Exercise $0 -36,606 -62% $0.000000 22,894 17 Dec 2025 Common Stock 36,606 $66.49 Direct F1, F7
transaction PTCT Stock Option (Right to Buy) Options Exercise $0 -3,684 -17% $0.000000 18,382 17 Dec 2025 Common Stock 3,684 $18.01 Direct F1, F7
transaction PTCT Stock Option (Right to Buy) Options Exercise $0 -2,951 -13% $0.000000 19,943 18 Dec 2025 Common Stock 2,951 $66.49 Direct F1, F7
transaction PTCT Stock Option (Right to Buy) Options Exercise $0 -251 -1.4% $0.000000 18,131 18 Dec 2025 Common Stock 251 $18.01 Direct F1, F7
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.

Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).

Explanation of Responses:

Id Content
F1 This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on September 15, 2025.
F2 This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $75.00 to $75.55 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.
F3 This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $75.00 to $75.99 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.
F4 This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $75.00 to $75.99 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.
F5 This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $75.00 to $75.18 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.
F6 This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $75.00 to $75.20 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.
F7 Currently exercisable.