Eric J. Loumeau - 16 Dec 2025 Form 4 Insider Report for ANAPTYSBIO, INC (ANAB)

Role
CHIEF LEGAL OFFICER
Signature
/s/ Eric Loumeau
Issuer symbol
ANAB
Transactions as of
16 Dec 2025
Net transactions value
-$665,925
Form type
4
Filing time
18 Dec 2025, 16:14:04 UTC
Previous filing
01 Oct 2025
Next filing
23 Dec 2025
SEC
View on sec.gov

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
LOUMEAU ERIC J CHIEF LEGAL OFFICER C/O ANAPTYSBIO, INC., 10770 WATERIDGE CIRCLE, SUITE 210, SAN DIEGO /s/ Eric Loumeau 18 Dec 2025 0001239648

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction ANAB Common Stock Options Exercise $70,100 +5,000 +55% $14.02 14,088 16 Dec 2025 Direct
transaction ANAB Common Stock Options Exercise $151,200 +7,500 +53% $20.16 21,588 16 Dec 2025 Direct
transaction ANAB Common Stock Sale $371,031 -8,305 -38% $44.68 13,283 16 Dec 2025 Direct F1, F2
transaction ANAB Common Stock Sale $189,769 -4,195 -32% $45.24 9,088 16 Dec 2025 Direct F1, F3
transaction ANAB Common Stock Options Exercise $140,200 +10,000 +110% $14.02 19,088 17 Dec 2025 Direct
transaction ANAB Common Stock Sale $460,000 -10,000 -52% $46.00 9,088 17 Dec 2025 Direct F1
transaction ANAB Common Stock Sale $6,626 -141 -1.6% $46.99 8,947 18 Dec 2025 Direct F1

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction ANAB Employee Stock Option (right to buy) Options Exercise $0 -5,000 -7.4% $0.000000 63,000 16 Dec 2025 Common Stock 5,000 $14.02 Direct F4
transaction ANAB Employee Stock Option (right to buy) Options Exercise $0 -7,500 -100% $0.000000 0 16 Dec 2025 Common Stock 7,500 $20.16 Direct F4
transaction ANAB Employee Stock Option (right to buy) Options Exercise $0 -10,000 -16% $0.000000 53,000 17 Dec 2025 Common Stock 10,000 $14.02 Direct F4, F5
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.

Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).

Explanation of Responses:

Id Content
F1 The transactions reported on this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the reporting person dated April 11, 2025.
F2 The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $44.12 to $45.11 per share, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
F3 The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $45.13 to $45.34 per share, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
F4 The stock option is fully vested.
F5 In addition to the options to purchase a total of 53,000 shares of common stock as set forth in Table II, the Reporting Person also holds additional options to purchase up to an aggregate of 414,810 shares of common stock, which options vest according to their terms.