| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| MAETZOLD DEREK J | Pres. & Chief Exec. Officer, Director | C/O CASTLE BIOSCIENCES, INC., 505 S. FRIENDSWOOD DRIVE, SUITE 401, FRIENDSWOOD | /s/ Frank Stokes, Attorney-in-Fact | 14 Jan 2026 | 0001239501 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | CSTL | Common Stock | Award | $0 | +62,219 | +211% | $0.000000 | 91,732 | 12 Jan 2026 | Direct | F1 |
| holding | CSTL | Common Stock | 52,923 | 12 Jan 2026 | By The Maetzold Descendants 2020 Trust | F2 | |||||
| holding | CSTL | Common Stock | 44,986 | 12 Jan 2026 | By Derek Maetzold 2020 Irrevocable Trust | F3 | |||||
| holding | CSTL | Common Stock | 3,618 | 12 Jan 2026 | By The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk | F4 | |||||
| holding | CSTL | Common Stock | 3,615 | 12 Jan 2026 | By The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold | F5 | |||||
| holding | CSTL | Common Stock | 3,615 | 12 Jan 2026 | By The Maetzold 2018 Remainder Trust FBO John Derek Maetzold | F6 | |||||
| holding | CSTL | Common Stock | 3,615 | 12 Jan 2026 | By The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold | F7 | |||||
| holding | CSTL | Common Stock | 85,959 | 12 Jan 2026 | By DJM Grantor Retained Annuity Trust No. 5 | F8 | |||||
| holding | CSTL | Common Stock | 18,718 | 12 Jan 2026 | By DJM Grantor Retained Annuity Trust No. 6 | F9 | |||||
| holding | CSTL | Common Stock | 44,323 | 12 Jan 2026 | By DJM Grantor Retained Annuity Trust No. 7 | F10 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | CSTL | Performance-Based Stock Unit | Award | $0 | +62,219 | $0.000000 | 62,219 | 12 Jan 2026 | Common Stock | 62,219 | Direct | F11 |
| Id | Content |
|---|---|
| F1 | Represents 50% of the Performance-Based Stock Units ("PSUs") granted on March 4, 2024 ("2024 PSUs") that vested based on the satisfaction of certain performance criteria as certified by the board of directors of the Issuer on January 12, 2026. |
| F2 | Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries. |
| F3 | Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries. |
| F4 | Held by The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk of which the Reporting Person is the trustee and his child is the beneficiary. |
| F5 | Held by The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold of which the Reporting Person is the trustee and his child is the beneficiary. |
| F6 | Held by The Maetzold 2018 Remainder Trust FBO John Derek Maetzold of which the Reporting Person is the trustee and his child is the beneficiary. |
| F7 | Held by The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold of which the Reporting Person is the trustee and his child is the beneficiary. |
| F8 | Held by DJM Grantor Retained Annuity Trust No. 5 of which the Reporting Person is the trustee and beneficiary. |
| F9 | Held by DJM Grantor Retained Annuity Trust No. 6 of which the Reporting Person is the trustee and the beneficiaries are The Maetzold 2018 Remainder Trust FBO John Derek Maetzold, The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk, The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold and The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold. |
| F10 | Held by DJM Grantor Retained Annuity Trust No. 7 of which the Reporting Person is the trustee and beneficiary. |
| F11 | Each PSU represents the right to receive one share of the Issuer's Common Stock. These PSUs represent the remaining 50% of the 2024 PSUs which will vest subject to the achievement of certain milestones. |