| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| MAETZOLD DEREK J | Pres. & Chief Exec. Officer, Director | C/O CASTLE BIOSCIENCES, INC., 505 S. FRIENDSWOOD DRIVE, SUITE 401, FRIENDSWOOD | /s/ Frank Stokes, Attorney-in-fact | 2025-08-12 | 0001239501 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | CSTL | Common Stock | Options Exercise | $0 | +67K | +96.14% | $0.00 | 137K | Aug 8, 2025 | Direct | F1 |
| transaction | CSTL | Common Stock | Tax liability | -$464K | -24K | -17.54% | $19.36 | 113K | Aug 8, 2025 | Direct | |
| holding | CSTL | Common Stock | 52.9K | Aug 8, 2025 | By The Maetzold Descendants 2020 Trust | F2 | |||||
| holding | CSTL | Common Stock | 45K | Aug 8, 2025 | By Derek Maetzold 2020 Irrevocable Trust | F3 | |||||
| holding | CSTL | Common Stock | 3.62K | Aug 8, 2025 | By The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk | F4 | |||||
| holding | CSTL | Common Stock | 3.62K | Aug 8, 2025 | By The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold | F5 | |||||
| holding | CSTL | Common Stock | 3.62K | Aug 8, 2025 | By The Maetzold 2018 Remainder Trust FBO John Derek Maetzold | F6 | |||||
| holding | CSTL | Common Stock | 3.62K | Aug 8, 2025 | By The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold | F7 | |||||
| holding | CSTL | Common Stock | 86K | Aug 8, 2025 | By DJM Grantor Retained Annuity Trust No. 5 | F1, F8 | |||||
| holding | CSTL | Common Stock | 18.7K | Aug 8, 2025 | By DJM Grantor Retained Annuity Trust No. 6 | F1, F9 | |||||
| holding | CSTL | Common Stock | 44.3K | Aug 8, 2025 | By DJM Grantor Retained Annuity Trust No. 7 | F1, F10 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | CSTL | Performance-Based Stock Unit | Options Exercise | $0 | -67K | -100% | $0.00 | 0 | Aug 8, 2025 | Common Stock | 67K | Direct | F11 |
| Id | Content |
|---|---|
| F1 | Reflects the transfers on July 11, 2025, of 36,907 shares of common stock from DJM Grantor Annuity Trust No. 5 and 7,416 shares of common stock from DJM Grantor Annuity Trust No. 6 to the Reporting Person's direct holdings, and the transfer on July 14, 2025, of 44,323 shares of common stock from the Reporting Person's direct holdings to DJM Grantor Annuity Trust No. 7. |
| F2 | Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries. |
| F3 | Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries. |
| F4 | Held by The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk of which the Reporting Person is the trustee and his child is the beneficiary. |
| F5 | Held by The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold of which the Reporting Person is the trustee and his child is the beneficiary. |
| F6 | Held by The Maetzold 2018 Remainder Trust FBO John Derek Maetzold of which the Reporting Person is the trustee and his child is the beneficiary. |
| F7 | Held by The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold of which the Reporting Person is the trustee and his child is the beneficiary. |
| F8 | Held by DJM Grantor Retained Annuity Trust No. 5 of which the Reporting Person is the trustee and beneficiary. |
| F9 | Held by DJM Grantor Retained Annuity Trust No. 6 of which the Reporting Person is the trustee and the beneficiaries are The Maetzold 2018 Remainder Trust FBO John Derek Maetzold, The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk, The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold and The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold. |
| F10 | Held by DJM Grantor Retained Annuity Trust No. 7 of which the Reporting Person is the trustee and beneficiary. |
| F11 | Each Performance-Based Stock Unit ("PSU") represents the right to receive one share of the Issuer's Common Stock. These PSUs represent the remaining 50% of the PSUs granted on December 23, 2022, which were all subject to time-based vesting and vested in full on the one-year anniversary of August 9, 2024. |