Alistair Milnes - 25 Mar 2022 Form 4 Insider Report for BICYCLE THERAPEUTICS plc (BCYC)

Role: Chief Operating Officer
Signature: /s/ Lee Kalowski, Attorney-in-Fact
Issuer symbol: BCYC
Transactions as of: 25 Mar 2022
Net transactions value: +$103,719
Form type: 4
Filing time: 29 Mar 2022, 16:36:19 UTC
Previous filing: 29 Mar 2022
Next filing: 05 Jan 2023
SEC: View on sec.gov

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	BCYC	Ordinary Shares	Options Exercise	$103,719	+5,155	+30%	$20.12	22,480	25 Mar 2022	Direct

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	BCYC	Employee Stock Option (right to buy)	Options Exercise	$0	+5,155	+12%	$0.000000	46,845	25 Mar 2022	Ordinary Shares	5,155	$20.12	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	This option vested one-fourth (1/4) of the total number of shares underlying the option on January 4, 2022 and the remaining shares in 36 equal monthly installments thereafter.