Sharon Shacham - Feb 28, 2022 Form 4 Insider Report for Karyopharm Therapeutics Inc. (KPTI)

Signature
/s/ Nancy Smith as Attorney-in-Fact for Sharon Shacham
Stock symbol
KPTI
Transactions as of
Feb 28, 2022
Transactions value $
-$127,477
Form type
4
Date filed
3/2/2022, 02:20 PM
Previous filing
Feb 22, 2022
Next filing
Mar 31, 2022

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction KPTI Common Stock Sale -$63.7K -6.23K -0.69% $10.24* 898K Feb 28, 2022 Direct F1, F2
transaction KPTI Common Stock Award $0 +21K +3% $0.00 720K Feb 28, 2022 By Spouse F3
transaction KPTI Common Stock Sale -$63.7K -6.23K -0.86% $10.24* 714K Feb 28, 2022 By Spouse F2, F4

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction KPTI Stock Option (right to buy) Award $0 +27K $0.00 27K Feb 28, 2022 Common Stock 27K $10.33 By Spouse F5
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id Content
F1 This transaction was a broker-assisted sale of shares to satisfy the payment of withholding tax liability incurred upon the vesting of restricted stock units and does not represent a discretionary trade by the reporting person.
F2 Represents the weighted average sale price. These shares were sold in multiple transactions at prices ranging from $10.24 to $10.35, inclusive. The reporting person undertakes to provide upon request by the U.S. Securities and Exchange Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price.
F3 Represents the award of restricted stock units ("RSUs") to the spouse of the reporting person pursuant to the Karyopharm Therapeutics Inc. 2013 Stock Incentive Plan (the "Plan"). RSUs convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis. The RSUs vest in four equal annual installments beginning February 28, 2023.
F4 This transaction was a broker-assisted sale of shares to satisfy the payment of withholding tax liability incurred upon the vesting of restricted stock units and does not represent a discretionary trade by the spouse of the reporting person.
F5 This option was granted to the spouse of the reporting person on February 28, 2022 pursuant to the Plan. The shares underlying this option vest as to 25% of the shares on February 28, 2023, with the remaining 75% vesting in 36 equal monthly installments thereafter.