Nicholas Keen - Jan 3, 2022 Form 4 Insider Report for BICYCLE THERAPEUTICS plc (BCYC)

Role: Chief Scientific Officer
Signature: /s/ Lee Kalowski, Attorney-in-Fact
Stock symbol: BCYC
Transactions as of: Jan 3, 2022
Transactions value $: $0
Form type: 4
Date filed: 1/5/2022, 04:21 PM
Previous filing: Dec 22, 2021
Next filing: Jan 5, 2023

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	BCYC	Ordinary Shares	Award	$0	+15K	+176.95%	$0.00	23.5K	Jan 3, 2022	Direct	F1, F2
holding	BCYC	Ordinary Shares						7K	Jan 3, 2022	By GRAT

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	BCYC	Employee Stock Option (right to buy)	Award	$0	+30K		$0.00	30K	Jan 3, 2022	Ordinary Shares	30K	$60.87	Direct	F3

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Represents a restricted stock unit ("RSU") award. One-fourth (1/4) of the total number of RSUs shall vest on January 3, 2023 and the remaining RSUs shall vest in 12 equal quarterly installments thereafter.
F2	Each RSU represents a contingent right to receive one ordinary share.
F3	This option shall vest one-fourth (1/4) of the total number of shares underlying the option on January 3, 2023 and the remaining shares in 36 equal monthly installments thereafter.