Nicholas Keen - 03 Jan 2022 Form 4 Insider Report for BICYCLE THERAPEUTICS plc (BCYC)

Role: Chief Scientific Officer
Signature: /s/ Lee Kalowski, Attorney-in-Fact
Issuer symbol: BCYC
Transactions as of: 03 Jan 2022
Net transactions value: $0
Form type: 4
Filing time: 05 Jan 2022, 16:21:51 UTC
Previous filing: 22 Dec 2021
Next filing: 05 Jan 2023
SEC: View on sec.gov

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	BCYC	Ordinary Shares	Award	$0	+15,000	+177%	$0.000000	23,477	03 Jan 2022	Direct	F1, F2
holding	BCYC	Ordinary Shares						7,000	03 Jan 2022	By GRAT

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	BCYC	Employee Stock Option (right to buy)	Award	$0	+30,000		$0.000000	30,000	03 Jan 2022	Ordinary Shares	30,000	$60.87	Direct	F3

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Represents a restricted stock unit ("RSU") award. One-fourth (1/4) of the total number of RSUs shall vest on January 3, 2023 and the remaining RSUs shall vest in 12 equal quarterly installments thereafter.
F2	Each RSU represents a contingent right to receive one ordinary share.
F3	This option shall vest one-fourth (1/4) of the total number of shares underlying the option on January 3, 2023 and the remaining shares in 36 equal monthly installments thereafter.