Patrick O'Brien - 31 Dec 2021 Form 4 Insider Report for ARROWHEAD PHARMACEUTICALS, INC. (ARWR)

Role: General Counsel
Signature: /s/ Patrick O'Brien
Issuer symbol: ARWR
Transactions as of: 31 Dec 2021
Net transactions value: +$172,200
Form type: 4
Filing time: 04 Jan 2022, 20:26:24 UTC
Next filing: 07 Jan 2022
SEC: View on sec.gov

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	ARWR	Common Stock	Options Exercise	$172,200	+28,000	+9.5%	$6.15^*	321,375	31 Dec 2021	Direct
transaction	ARWR	Common Stock	Award	$0	+60,000	+19%	$0.000000	381,375	01 Jan 2022	Direct	F1, F2

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	ARWR	Stock Option (right to buy Common Stock)	Options Exercise	$0	-28,000	-47%	$0.000000	32,000	31 Dec 2021	Common Stock	28,000	$6.15	Direct	F3

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Represents shares underlying a restricted stock unit, which shares will vest in four equal annual installments.
F2	Includes previously reported shares of common stock underlying Restricted Stock Units granted to the Reporting person which are subject to certain vesting conditions.
F3	Represents the first vesting date. Option vested over four years from date of grant.