Patrick O'Brien - Dec 31, 2021 Form 4 Insider Report for ARROWHEAD PHARMACEUTICALS, INC. (ARWR)

Role: General Counsel
Signature: /s/ Patrick O'Brien
Stock symbol: ARWR
Transactions as of: Dec 31, 2021
Transactions value $: $172,200
Form type: 4
Date filed: 1/4/2022, 08:26 PM
Next filing: Jan 7, 2022

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	ARWR	Common Stock	Options Exercise	$172K	+28K	+9.54%	$6.15^*	321K	Dec 31, 2021	Direct
transaction	ARWR	Common Stock	Award	$0	+60K	+18.67%	$0.00	381K	Jan 1, 2022	Direct	F1, F2

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	ARWR	Stock Option (right to buy Common Stock)	Options Exercise	$0	-28K	-46.67%	$0.00	32K	Dec 31, 2021	Common Stock	28K	$6.15	Direct	F3

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Represents shares underlying a restricted stock unit, which shares will vest in four equal annual installments.
F2	Includes previously reported shares of common stock underlying Restricted Stock Units granted to the Reporting person which are subject to certain vesting conditions.
F3	Represents the first vesting date. Option vested over four years from date of grant.