Lawrence Klein - Sep 10, 2021 Form 4 Insider Report for CRISPR Therapeutics AG (CRSP)

Role: CBO & COO
Signature: /s/ Michael Esposito, attorney-in-fact
Stock symbol: CRSP
Transactions as of: Sep 10, 2021
Transactions value $: -$495,837
Form type: 4
Date filed: 9/14/2021, 09:44 PM
Previous filing: May 27, 2021
Next filing: Oct 1, 2021

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	CRSP	Common Shares	Options Exercise		+10K	+952.38%		11.1K	Sep 10, 2021	Direct	F1, F2
transaction	CRSP	Common Shares	Tax liability	-$496K	-4.21K	-38.07%	$117.86	6.84K	Sep 13, 2021	Direct	F3

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	CRSP	Restricted Stock Units	Tax liability		-10K	-100%		0	Sep 10, 2021	Common Shares	10K		Direct	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The restricted stock unit award was granted on September 10, 2019 with respect to 10,000 Common Shares, with all shares vesting on September 10, 2021.
F2	Each restricted stock unit represents a contingent right to receive one share of CRSP Common Shares.
F3	Amount reported represents the number of shares required to be sold by the reporting person to cover the tax withholding obligation in connection with the vesting of these restricted stock units. This sale is mandated by the Company's RSU Settlement Policy to fund the tax withholding obligation and does not represent a discretionary trade by the reporting person.