Lee Kalowski - 02 Sep 2021 Form 4 Insider Report for BICYCLE THERAPEUTICS plc (BCYC)

Role: President and CFO
Signature: /s/ Lee Kalowski
Issuer symbol: BCYC
Transactions as of: 02 Sep 2021
Net transactions value: -$301,800
Form type: 4
Filing time: 03 Sep 2021, 16:49:09 UTC
Previous filing: 27 Aug 2021
Next filing: 05 Jan 2022
SEC: View on sec.gov

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	BCYC	Ordinary Shares	Options Exercise	$98,200	+10,000		$9.82	10,000	02 Sep 2021	Direct	F1
transaction	BCYC	Ordinary Shares	Sale	$400,000	-10,000	-100%	$40.00	0	02 Sep 2021	Direct	F1

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	BCYC	Employee Stock Option (right to buy)	Options Exercise	$0	-10,000	-17%	$0.000000	50,000	02 Sep 2021	Ordinary Shares	10,000	$9.82	Direct	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Shares exercised and sold pursuant to a Rule 10b5-1 trading plan.
F2	This option shall vest one-fourth (1/4) of the total number of shares under option on January 2, 2021 and the remaining shares in 36 equal monthly installments at the end of each calendar month thereafter.