Nigel Crockett - Jul 6, 2021 Form 4 Insider Report for BICYCLE THERAPEUTICS plc (BCYC)

Role: Chief Business Officer
Signature: /s/ Lee Kalowski, Attorney-in-Fact
Stock symbol: BCYC
Transactions as of: Jul 6, 2021
Transactions value $: -$6,011
Form type: 4
Date filed: 7/8/2021, 05:22 PM
Next filing: Jul 14, 2021

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	BCYC	Ordinary Shares	Options Exercise	$2.66K	+271		$9.82	271	Jul 6, 2021	Direct
transaction	BCYC	Ordinary Shares	Sale	-$8.67K	-271	-100%	$32.00	0	Jul 6, 2021	Direct	F1

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	BCYC	Employee Stock Option (right to buy)	Options Exercise	$0	-271	-0.45%	$0.00	59.7K	Jul 6, 2021	Ordinary Shares	271	$9.82	Direct	F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Shares sold pursuant to a Rule 10b5-1 trading plan.
F2	This option shall vest one-fourth (1/4) of the total number of shares under option on January 2, 2021 and the remaining shares in 36 equal monthly installments at the end of each calendar month therafter.