Novo Holdings A/S - 19 May 2021 Form 4 Insider Report for SPRUCE BIOSCIENCES, INC. (SPRB)

Role: 10%+ Owner
Signature: /s/ Peter Haahr, Chief Financial Officer of Novo Holdings A/S
Issuer symbol: SPRB
Transactions as of: 19 May 2021
Net transactions value: -$6,602,500
Form type: 4
Filing time: 21 May 2021, 16:32:39 UTC
Next filing: 03 Jun 2021
SEC: View on sec.gov

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	SPRB	COMMON STOCK	Sale	$6,602,500	-475,000	-9.5%	$13.90	4,514,336	19 May 2021	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The securities were sold as a block sale broker transaction.

Remarks:

Novo Holdings A/S is a Danish limited liability company. The board of directors of Novo Holdings A/S (the "Novo Board") has shared investment and voting control over the securities of the Issuer held by Novo Holdings A/S (the "Shares") and may exercise such control only with the support of a majority of the Novo Board. As such, no individual member of the Novo Board is deemed to hold any beneficial ownership or reportable pecuniary interest in the Shares.