| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Harris Todd | President and CEO, Director | C/O TYRA BIOSCIENCES, INC., 2656 STATE STREET, CARLSBAD | /s/ Ali D. Fawaz, Attorney-in-Fact | 17 Mar 2026 | 0001711463 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | TYRA | Common Stock | Award | +1,463 | +0.11% | $9.13* | 1,358,631 | 13 Mar 2026 | Direct | F1 |
| Id | Content |
|---|---|
| F1 | These shares were acquired under the Issuer's 2021 Employee Stock Purchase Plan. |