Todd Harris - 07 Aug 2025 Form 4 Insider Report for Tyra Biosciences, Inc. (TYRA)

Role: President and CEO, Director
Signature: /s/ Ali D. Fawaz, Attorney-in-Fact
Issuer symbol: TYRA
Transactions as of: 07 Aug 2025
Net transactions value: $0
Form type: 4
Filing time: 07 Aug 2025, 16:36:24 UTC
Previous filing: 18 Mar 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Harris Todd	President and CEO, Director	C/O TYRA BIOSCIENCES, INC., 2656 STATE STREET, CARLSBAD	/s/ Ali D. Fawaz, Attorney-in-Fact	07 Aug 2025	0001711463

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	TYRA	Stock Option (Right to Buy)	Award	$0	+570,000		$0.000000	570,000	07 Aug 2025	Common Stock	570,000	$10.75	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	1/48th of the shares subject to the option vest monthly following August 7, 2025, the vesting commencement date, subject to the Reporting Person's continuous service to the Issuer through each vesting date.