| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Condella Sarah | EVP, Human Resources | C/O EXACT SCIENCES CORP., 5505 ENDEAVOR LANE, MADISON | /s/ Sarah Condella by Mark Busch, attorney-in- fact | 03 Mar 2026 | 0001839989 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | EXAS | Common Stock | Options Exercise | $19,617 | +3,900 | +3% | $5.03 | 133,034 | 27 Feb 2026 | Direct | |
| transaction | EXAS | Common Stock | Tax liability | $197,766 | -1,913 | -1.4% | $103.38 | 131,121 | 27 Feb 2026 | Direct | F1, F2 |
| holding | EXAS | Common Stock | 6,368 | 27 Feb 2026 | Held in 401(k) Plan |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | EXAS | Stock Options (Right to Buy) | Options Exercise | $0 | -3,900 | -100% | $0.000000 | 0 | 27 Feb 2026 | Common Stock | 3,900 | $5.03 | Direct | F3 |
| Id | Content |
|---|---|
| F1 | Represents shares of Common Stock retained by Exact Sciences Corporation for tax withholding purposes in connection with the net-settlement on the issuance of shares of Common Stock in respect to the exercise of certain stock options. |
| F2 | In addition to the shares of Common Stock reported on this Form 4, which total 137,489 shares, Ms. Condella also holds, in the aggregate, an additional 71,243 vested and unvested options to purchase shares of Common Stock and restricted stock units, with each restricted stock unit representing a contingent right to receive one share of Common Stock. |
| F3 | These options vested and became exercisable in full on February 28, 2020. |