| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Condella Sarah | EVP, Human Resources | C/O EXACT SCIENCES CORP., 5505 ENDEAVOR LANE, MADISON | /s/ Sarah Condella by Mark Busch, attorney-in- fact | 27 Feb 2026 | 0001839989 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| holding | EXAS | Common Stock | 129,134 | 25 Feb 2026 | Direct | F1 | |||||
| holding | EXAS | Common Stock | 6,355 | 25 Feb 2026 | Held in 401(k) Plan |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | EXAS | Restricted Stock Units | Award | $0 | +23,224 | $0.000000 | 23,224 | 25 Feb 2026 | Common Stock | 23,224 | Direct | F2, F3 |
| Id | Content |
|---|---|
| F1 | In addition to the shares of Common Stock reported on this Form 4, which total 135,489 shares, Ms. Condella also holds, in the aggregate, an additional 75,143 vested and unvested options to purchase shares of Common Stock and restricted stock units, with each restricted stock unit representing a contingent right to receive one share of Common Stock. |
| F2 | Each restricted stock unit represents a contingent right to receive one share of common stock. |
| F3 | These restricted stock units vest in four equal annual installments beginning on February 25, 2027. |