Foresite Capital Management IV, LLC - 04 Feb 2026 Form 3 Insider Report for Eikon Therapeutics, Inc. (EIKN)

Role: 10%+ Owner
Signature: Foresite Capital Fund IV, L.P., By: Foresite Capital Management IV, LLC, its General Partner, By: James B. Tananbaum, Managing Member /s/ James B. Tananbaum
Issuer symbol: EIKN
Transactions as of: 04 Feb 2026
Net transactions value: $0
Form type: 3
Filing time: 04 Feb 2026, 21:35:20 UTC
Previous filing: 05 Apr 2024
SEC: View on sec.gov

Reporting Owners (8)

Name	Relationship	Address	Signature	Signature date	CIK
Foresite Capital Management IV, LLC	10%+ Owner	C/O FORESITE CAPITAL MANAGEMENT, 9200 SUNSET BLVD SUITE 515, WEST HOLLYWOOD	Foresite Capital Fund IV, L.P., By: Foresite Capital Management IV, LLC, its General Partner, By: James B. Tananbaum, Managing Member /s/ James B. Tananbaum	04 Feb 2026	0001704132
Foresite Capital Fund IV, L.P.	10%+ Owner	C/O FORESITE CAPITAL MANAGEMENT, 9200 SUNSET BLVD SUITE 515, WEST HOLLYWOOD	Foresite Capital Management IV, LLC, By: James B. Tananbaum, Managing Member /s/ James B. Tananbaum	04 Feb 2026	0001704131
Foresite Capital Fund V, L.P.	10%+ Owner	C/O FORESITE CAPITAL MANAGEMENT, 9200 SUNSET BLVD SUITE 515, WEST HOLLYWOOD	Foresite Capital Fund V, L.P., By: Foresite Capital Management V, LLC, its General Partner, By: James B. Tananbaum, Managing Member /s/ James B. Tananbaum	04 Feb 2026	0001792204
Foresite Capital Management V, LLC	10%+ Owner	C/O FORESITE CAPITAL MANAGEMENT, 9200 SUNSET BLVD SUITE 515, WEST HOLLYWOOD	Foresite Capital Management V, LLC, By: James B. Tananbaum, Managing Member /s/ James B. Tananbaum	04 Feb 2026	0001792206
Foresite Capital Opportunity Fund V, L.P.	10%+ Owner	C/O FORESITE CAPITAL MANAGEMENT, 9200 SUNSET BLVD SUITE 515, WEST HOLLYWOOD	Foresite Capital Opportunity Fund V, L.P., By: Foresite Capital Opportunity Management V, LLC, its General Partner, By: James B. Tananbaum, Managing Member /s/ James B. Tananbaum	04 Feb 2026	0001792205
Foresite Capital Opportunity Management V, LLC	10%+ Owner	C/O FORESITE CAPITAL MANAGEMENT, 9200 SUNSET BLVD SUITE 515, WEST HOLLYWOOD	Foresite Capital Opportunity Management V, LLC, By: James B. Tananbaum, Managing Member /s/ James B. Tananbaum	04 Feb 2026	0001792207
Foresite Capital VI-A, LLC	10%+ Owner	C/O FORESITE CAPITAL MANAGEMENT, 9200 SUNSET BLVD SUITE 515, WEST HOLLYWOOD	Foresite Capital Fund VI-A, LLC, By: Foresite Capital VI-A Management, LLC, its General Partner, By: James B. Tananbaum, Managing Member /s/ James B. Tananbaum	04 Feb 2026	0001899120
Foresite Capital VI-A Management, LLC	10%+ Owner	C/O FORESITE CAPITAL MANAGEMENT, 9200 SUNSET BLVD SUITE 515, WEST HOLLYWOOD	Foresite Capital VI-A Management, LLC, By: James B. Tananbaum, Managing Member /s/ James B. Tananbaum	04 Feb 2026	0001899218

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
holding	EIKN	Series A Preferred Stock							04 Feb 2026	Common Stock	1,340,878		See footnote	F1, F2
holding	EIKN	Series A-1 Preferred Stock							04 Feb 2026	Common Stock	335,521		See footnote	F2, F3
holding	EIKN	Series A-1 Preferred Stock							04 Feb 2026	Common Stock	697,885		See footnote	F3, F4
holding	EIKN	Series A-1 Preferred Stock							04 Feb 2026	Common Stock	348,942		See footnote	F3, F5
holding	EIKN	Series B-1 Preferred Stock							04 Feb 2026	Common Stock	37,855		See footnote	F2, F6
holding	EIKN	Series B-1 Preferred Stock							04 Feb 2026	Common Stock	37,855		See footnote	F4, F6
holding	EIKN	Series B-1 Preferred Stock							04 Feb 2026	Common Stock	37,855		See footnote	F5, F6
holding	EIKN	Series B-1 Preferred Stock							04 Feb 2026	Common Stock	408,725		See footnote	F6, F7
holding	EIKN	Series C Preferred Stock							04 Feb 2026	Common Stock	1,626		See footnote	F4, F8
holding	EIKN	Series C Preferred Stock							04 Feb 2026	Common Stock	922		See footnote	F5, F8
holding	EIKN	Series C-1 Preferred Stock							04 Feb 2026	Common Stock	67,207		See footnote	F4, F9
holding	EIKN	Series C-1 Preferred Stock							04 Feb 2026	Common Stock	38,133		See footnote	F5, F9
holding	EIKN	Series D Preferred Stock							04 Feb 2026	Common Stock	229,428		See footnote	F2, F10
holding	EIKN	Series D Preferred Stock							04 Feb 2026	Common Stock	458,855		See footnote	F4, F10
holding	EIKN	Warrants							04 Feb 2026	Common Stock	17,092	$43.59	See footnote	F2
holding	EIKN	Warrants							04 Feb 2026	Common Stock	34,185	$43.59	See footnote	F4

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The Series A Preferred Stock is convertible into Common Stock on a 1-for-7.4578 basis and has no expiration date. Upon the closing of the Issuer's initial public offering ("IPO"), all shares of Series A Preferred Stock will be converted into shares of Common Stock of the Issuer.
F2	The shares are held by Foresite Capital Fund IV, L.P ("Fund IV"). Foresite Capital Management IV, LLC ("FCM IV") is the general partner of Fund IV and may be deemed to have sole voting and dispositive power over the securities held by Fund IV. James B. Tananbaum is the managing member of FCM IV and may be deemed to share voting and dispositive power over such securities. Each of the Reporting Persons disclaims the existence of a "group," as defined in Rule 13d-5 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and, other than Fund IV, disclaims beneficial ownership of the shares held by Fund IV, except to the extent of such person's pecuniary interest in such securities.
F3	The Series A-1 Preferred Stock is convertible into Common Stock on a 1-for-7.4578 basis and has no expiration date. Upon the closing of the Issuer's IPO, all shares of Series A-1 Preferred Stock will be converted into shares of Common Stock of the Issuer.
F4	The shares are held by Foresite Capital Fund V, L.P. ("Fund V"). Foresite Capital Management V, LLC ("FCM V") is the general partner of Fund V and may be deemed to have sole voting and dispositive power over the securities held by Fund V. James B. Tananbaum is the managing member of FCM V and may be deemed to share voting and dispositive power over such securities. Each of the Reporting Persons disclaims the existence of a "group," as defined in Rule 13d-5 of the Exchange Act, and, other than Fund V, disclaims beneficial ownership of the shares held by Fund V, except to the extent of such person's pecuniary interest in such securities.
F5	The shares are held by Foresite Capital Opportunity Fund V, L.P. ("Opportunity Fund V"). Foresite Capital Opportunity Management V, LLC ("FCOM V") is the general partner of Opportunity Fund V and may be deemed to have sole voting and dispositive power over the shares held by Opportunity Fund V. James B. Tananbaum is the managing member of FCOM V and may be deemed to share voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group," as defined in Rule 13d-5 of the Exchange Act, and, other than Opportunity Fund V, disclaims beneficial ownership of the shares held by Opportunity Fund V, except to the extent of such person's pecuniary interest in such securities.
F6	The Series B-1 Preferred Stock is convertible into Common Stock on a 1-for-7.4578 basis and has no expiration date. Upon the closing of the Issuer's IPO, all shares of Series B-1 Preferred Stock will be converted into shares of Common Stock of the Issuer.
F7	The shares are held by Foresite Capital VI-A, LLC ("Fund VI-A"). Foresite Capital VI-A Management, LLC ("FC VI-A Management") is the managing member of Fund VI-A and may be deemed to have sole voting and dispositive power over the shares held by Fund VI-A. James B. Tananbaum is the managing member of FC VI-A Management and may be deemed to share voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group," as defined in Rule 13d-5 of the Exchange Act, and, other than Fund VI-A, disclaims beneficial ownership of the shares held by Fund VI-A, except to the extent of such person's pecuniary interest in such securities.
F8	The Series C Preferred Stock is convertible into Common Stock on a 1-for-7.4578 basis and has no expiration date. Upon the closing of the Issuer's IPO, all shares of Series C Preferred Stock will be converted into shares of Common Stock of the Issuer.
F9	The Series C-1 Preferred Stock is convertible into Common Stock on a 1-for-7.4578 basis and has no expiration date. Upon the closing of the Issuer's IPO, all shares of Series C-1 Preferred Stock will be converted into shares of Common Stock of the Issuer.
F10	The Series D Preferred Stock is convertible into Common Stock on a 1-for 7.4578 basis and has no expiration date. Upon the closing of the Issuer's IPO, all shares of Series D Preferred Stock will be converted into shares of Common Stock of the Issuer.