| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Patel Naimish | Chief Medical Officer | C/O CRISPR THERAPEUTICS, 105 WEST FIRST STREET, BOSTON | /s/ Naimish Patel | 27 Jan 2026 | 0002021679 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | CRSP | Common Shares | Purchase | $49,704 | +1,508 | $32.96 | 1,508 | 03 Apr 2025 | Direct | F1 |
| Id | Content |
|---|---|
| F1 | The purchase of Common Shares reported herein was matchable under Section 16(b) of the Securities Exchange Act of 1934, to the extent of 1,508 shares, with a subsequent sale of Common Shares at a price of $35.94 per share on May 29, 2025 pursuant to a mandatory "sell to cover" provision in an award agreement covering a restricted stock unit that vested on such date (and which was reported on a separate Form 4 filing dated May 30, 2025). The Reporting Person has agreed to pay to the Issuer $4,493.84, representing the full amount of the profit realized in connection with the short-swing transaction. |