Ryan Martins - 22 Oct 2025 Form 4 Insider Report for 89bio, Inc. (ETNB)

Role
Chief Financial Officer
Signature
/s/ Ryan A. Murr, as attorney-in-fact for Ryan Martins
Issuer symbol
ETNB
Transactions as of
22 Oct 2025
Net transactions value
+$256,469
Form type
4
Filing time
23 Oct 2025, 17:10:23 UTC
Previous filing
05 Aug 2025
Next filing
30 Oct 2025
SEC
View on sec.gov

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
Martins Ryan Chief Financial Officer C/O 89BIO, INC., 655 MONTGOMERY STREET, SUITE 1500, SAN FRANCISCO /s/ Ryan A. Murr, as attorney-in-fact for Ryan Martins 23 Oct 2025 0001792018

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction ETNB Common Stock Options Exercise $239,162 +76,901 +30% $3.11 335,397 22 Oct 2025 Direct F1
transaction ETNB Common Stock Options Exercise $17,307 +3,898 +1.2% $4.44 339,295 22 Oct 2025 Direct

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction ETNB Stock Option (Right to Buy) Options Exercise $0 -76,901 -100% $0.000000 0 22 Oct 2025 Common Stock 76,901 $3.11 Direct F2, F3
transaction ETNB Stock Option (Right to Buy) Options Exercise $0 -3,898 -7.5% $0.000000 48,102 22 Oct 2025 Common Stock 3,898 $4.44 Direct F4
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id Content
F1 Due to an administrative error, the exercise of an aggregate of 5,000 options was erroneously omitted from the Form 4 filed by the Reporting Person on March 27, 2023. This form reflects the correct amount of common stock owned by the Reporting Person.
F2 This option is vested in full.
F3 Due to an administrative error, the exercise of an aggregate of 5,000 options was erroneously omitted from the Form 4 filed by the Reporting Person on March 27, 2023. This form reflects the correct amount of stock options owned by the Reporting Person.
F4 This option represents a right to purchase a total of 52,000 shares of the Issuer's Common Stock, one quarter of which vested on February 17, 2023, with the remaining three quarters vesting in equal quarterly installments over the following three years, subject to the Reporting Person's continued service to the Issuer.