Wendy McDermott - Feb 28, 2023 Form 4 Insider Report for LEXICON PHARMACEUTICALS, INC. (LXRX)

Role: VP, Human Resources
Signature: /s/ Wendy E. McDermott
Stock symbol: LXRX
Transactions as of: Feb 28, 2023
Transactions value $: -$14,029
Form type: 4
Date filed: 3/1/2023, 03:54 PM
Previous filing: Feb 13, 2023
Next filing: Jun 27, 2023

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	LXRX	Common Stock	Options Exercise		+18.9K			18.9K	Feb 28, 2023	Direct	F1
transaction	LXRX	Common Stock	Tax liability	-$14K	-6.47K	-34.13%	$2.17	12.5K	Feb 28, 2023	Direct	F2

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	LXRX	Restricted Stock Units	Options Exercise		-18.9K	-33.33%		37.9K	Feb 28, 2023	Common Stock	18.9K		Direct	F1, F3

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Each restricted stock unit represents a contingent right to receive one share of common stock.
F2	Withholding of a portion of issued shares by the Company in satisfaction of shareholder's tax withholding obligations with respect thereto.
F3	Restricted stock units vest with respect to 1/3 of the shares subject to the restricted stock units on February 28 of each of the three years following the year of grant.