Eric Paul Lefkofsky - 18 Nov 2025 Form 4 Insider Report for Tempus AI, Inc. (TEM)

Role
CEO and Chairman, Director, 10%+ Owner
Signature
/s/ Andrew Polovin, Attorney-in-Fact
Issuer symbol
TEM
Transactions as of
18 Nov 2025
Net transactions value
-$12,569,043
Form type
4
Filing time
20 Nov 2025, 19:56:06 UTC
Previous filing
30 Oct 2025
Next filing
25 Nov 2025
SEC
View on sec.gov

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
LEFKOFSKY ERIC P CEO and Chairman, Director, 10%+ Owner C/O TEMPUS AI, INC., 600 WEST CHICAGO AVENUE, SUITE 510, CHICAGO /s/ Andrew Polovin, Attorney-in-Fact 20 Nov 2025 0001114357

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction TEM Class A Common Stock Sale $754,862 -11,567 -0.57% $65.26 2,008,475 18 Nov 2025 Direct F1, F2
transaction TEM Class A Common Stock Sale $348,081 -5,262 -0.26% $66.15 2,003,213 18 Nov 2025 Direct F1, F3
transaction TEM Class A Common Stock Sale $408,035 -6,221 -0.07% $65.59 9,068,312 20 Nov 2025 By Gray Media, LLC F4, F5, F6
transaction TEM Class A Common Stock Sale $428,956 -6,467 -0.07% $66.33 9,061,845 20 Nov 2025 By Gray Media, LLC F4, F6, F7
transaction TEM Class A Common Stock Sale $128,917 -1,913 -0.02% $67.39 9,059,932 20 Nov 2025 By Gray Media, LLC F4, F6, F8
transaction TEM Class A Common Stock Sale $62,226 -910 -0.01% $68.38 9,059,022 20 Nov 2025 By Gray Media, LLC F4, F6, F9
transaction TEM Class A Common Stock Sale $141,707 -2,041 -0.02% $69.43 9,056,981 20 Nov 2025 By Gray Media, LLC F4, F6, F10
transaction TEM Class A Common Stock Sale $216,963 -3,074 -0.03% $70.58 9,053,907 20 Nov 2025 By Gray Media, LLC F4, F6, F11
transaction TEM Class A Common Stock Sale $633,281 -8,841 -0.1% $71.63 9,045,066 20 Nov 2025 By Gray Media, LLC F4, F6, F12
transaction TEM Class A Common Stock Sale $273,133 -3,783 -0.04% $72.20 9,041,283 20 Nov 2025 By Gray Media, LLC F4, F6, F13
transaction TEM Class A Common Stock Sale $1,631,945 -24,881 -0.15% $65.59 16,812,588 20 Nov 2025 By Blue Media, LLC F4, F5, F6, F14
transaction TEM Class A Common Stock Sale $1,715,692 -25,866 -0.15% $66.33 16,786,722 20 Nov 2025 By Blue Media, LLC F4, F6, F7
transaction TEM Class A Common Stock Sale $516,207 -7,660 -0.05% $67.39 16,779,062 20 Nov 2025 By Blue Media, LLC F4, F6, F8
transaction TEM Class A Common Stock Sale $248,903 -3,640 -0.02% $68.38 16,775,422 20 Nov 2025 By Blue Media, LLC F4, F6, F9
transaction TEM Class A Common Stock Sale $566,410 -8,158 -0.05% $69.43 16,767,264 20 Nov 2025 By Blue Media, LLC F4, F6, F10
transaction TEM Class A Common Stock Sale $867,781 -12,295 -0.07% $70.58 16,754,969 20 Nov 2025 By Blue Media, LLC F4, F6, F11
transaction TEM Class A Common Stock Sale $2,532,980 -35,362 -0.21% $71.63 16,719,607 20 Nov 2025 By Blue Media, LLC F4, F6, F12
transaction TEM Class A Common Stock Sale $1,092,964 -15,138 -0.09% $72.20 16,704,469 20 Nov 2025 By Blue Media, LLC F4, F6, F13
holding TEM Class A Common Stock 406 18 Nov 2025 By 346 Long LLC F6
holding TEM Class A Common Stock 10,000,000 18 Nov 2025 Lefkofsky Family 2025 GRAT F6
holding TEM Class A Common Stock 206 18 Nov 2025 By Black Media, LLC F6
holding TEM Class A Common Stock 832,131 18 Nov 2025 By Lefkofsky Family Foundation F6, F14
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.

Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).

Explanation of Responses:

Id Content
F1 Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting of the restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of minimum statutory tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary sale by the Reporting Person.
F2 The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $64.7216 to $65.685 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2), (3), (5), (7), (8), (9), (10), (11), (12) and (13).
F3 The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $65.78 to $66.62 inclusive.
F4 This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 4, 2025.
F5 The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $64.94 to $65.935 inclusive.
F6 The Reporting Person is (i) a member of, and controls a limited liability company that is a member of, 346 Long LLC, (ii) the sole manager of each of Black Media, LLC, Blue Media, LLC and Gray Media, LLC and (iii) a trustee of Lefkofsky Family Foundation. The Reporting Person's spouse is the trustee of the Lefkofsky Family 2025 GRAT.
F7 The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $65.94 to $66.935 inclusive.
F8 The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $66.94 to $67.93 inclusive.
F9 The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $67.94 to $68.835 inclusive.
F10 The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $69.00 to $69.90 inclusive.
F11 The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $70.05 to $71.04 inclusive.
F12 The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $71.065 to $72.06 inclusive.
F13 The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $72.065 to $72.40 inclusive.
F14 Represents the number of shares owned after Blue Media, LLC contributed a portion of its shares to the Lefkofsky Family Foundation.