| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Waddill William D. | Director | C/O PROTAGONIST THERAPEUTICS, INC., 7707 GATEWAY BLVD., SUITE 140, NEWARK | /s/ Matthew Gosling, Attorney-in-Fact for William D. Waddill | 06 Feb 2026 | 0001553338 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | PTGX | Common Stock | Options Exercise | $166,200 | +20,000 | +256% | $8.31 | 27,825 | 06 Feb 2026 | Direct | |
| transaction | PTGX | Common Stock | Sale | $1,673,600 | -20,000 | -72% | $83.68 | 7,825 | 06 Feb 2026 | Direct | F1 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | PTGX | Stock Option (right to buy) | Options Exercise | $0 | -20,000 | -100% | $0.000000 | 0 | 06 Feb 2026 | Common Stock | 20,000 | $8.31 | Direct | F2 |
| Id | Content |
|---|---|
| F1 | The price reported represents the weighted average sale price per share. The shares were sold in multiple transactions at prices ranging from $83.65 to $83.87. Upon request by the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, the Reporting Person will provide full information regarding the number of shares sold at each separate price. |
| F2 | These stock options are fully vested. |