| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| PATEL DINESH V PH D | President and CEO, Director | C/O PROTAGONIST THERAPEUTICS, INC., 7707 GATEWAY BLVD., SUITE 140, NEWARK | /s/ Matthew Gosling, Attorney-in-Fact for Dinesh V. Patel, Ph.D. | 06 Jan 2026 | 0001120477 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | PTGX | Common Stock | Award | $0 | +95,400 | +18% | $0.000000 | 614,943 | 02 Jan 2026 | Direct | F1 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | PTGX | Stock Option (right to buy) | Award | $0 | +120,200 | $0.000000 | 120,200 | 02 Jan 2026 | Common Stock | 120,200 | $87.18 | Direct | F2 |
| Id | Content |
|---|---|
| F1 | Represents grant of restricted stock units payable solely in common stock that will vest in four equal annual installments on January 15, 2027, 2028, 2029 and 2030, subject to the Reporting Person's continued service to the Issuer through each applicable vesting date. |
| F2 | The stock option vests in 48 equal monthly installments following January 2, 2026, subject to the Reporting Person's continued service to the Issuer through each applicable vesting date. |