| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Hoffman Michael B | Director | C/O ANNOVIS BIO, INC., 101 LINDENWOOD DR, SUITE 225, MALVERN | /s/ Maria Maccecchini Attorney-in-Fact | 21 Nov 2025 | 0001290208 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | ANVS | Common Stock | Purchase | $34.9K | +10K | +0.4% | $3.49 | 2.48M | 21 Nov 2025 | Direct | |
| transaction | ANVS | Common Stock | Purchase | $35K | +10K | +0.4% | $3.50 | 2.49M | 21 Nov 2025 | Direct | |
| holding | ANVS | Common Stock | 223K | 21 Nov 2025 | The 2018 Jane and Michael Hoffman Descendants Trust | F1 |
| Id | Content |
|---|---|
| F1 | The shares are held in a family trust formed by the reporting person and the reporting person has voting and investment power over such shares. |