Michael Henderson - Nov 13, 2025 Form 4 Insider Report for Apogee Therapeutics, Inc. (APGE)

Role
Chief Executive Officer, Director
Signature
/s/ Matthew Batters, as attorney-in-fact for Michael Henderson
Stock symbol
APGE
Transactions as of
Nov 13, 2025
Transactions value $
-$1,260,236
Form type
4
Date filed
11/13/2025, 08:24 PM
Previous filing
Jun 2, 2025
Next filing
Dec 5, 2025
SEC
View on sec.gov

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
HENDERSON MICHAEL THOMAS Chief Executive Officer, Director C/O APOGEE THERAPEUTICS, INC., 221 CRESCENT ST., BLDG. 17, STE. 102B, WALTHAM /s/ Matthew Batters, as attorney-in-fact for Michael Henderson 2025-11-13 0001779990

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction APGE Common Stock Sale -$207K -3.34K -0.26% $61.93 1.29M Nov 13, 2025 Direct F1, F2
transaction APGE Common Stock Sale -$933K -14.8K -1.15% $63.14 1.27M Nov 13, 2025 Direct F1, F3
transaction APGE Common Stock Sale -$114K -1.79K -0.14% $63.89 1.27M Nov 13, 2025 Direct F1, F4
transaction APGE Common Stock Sale -$6.45K -100 -0.01% $64.52 1.27M Nov 13, 2025 Direct F1
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.

Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).

Explanation of Responses:

Id Content
F1 This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on August 13, 2025.
F2 The price reported above is a weighted average price. The shares were sold in multiple transactions at prices ranging from $61.45 to $62.39, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission (the "SEC"), upon request, full information regarding the number of shares sold at each separate price within the range.
F3 The price reported above is a weighted average price. The shares were sold in multiple transactions at prices ranging from $62.50 to $63.47, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the range.
F4 The price reported above is a weighted average price. The shares were sold in multiple transactions at prices ranging from $63.52 to $64.39, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the range.