Richard Ian Griffiths - 05 May 2025 Form 4 Insider Report for Silence Therapeutics plc (SLN)

Role: 10%+ Owner
Signature: /s/ Richard Ian Griffiths
Issuer symbol: SLN
Transactions as of: 05 May 2025
Net transactions value: $0
Form type: 4
Filing time: 08 May 2025, 07:08:00 UTC
Previous filing: 02 May 2025
Next filing: 15 May 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Griffiths Richard Ian	10%+ Owner	FLOOR 1 LIBERATION STATION, ESPLANADE, ST HELIER, JERSEY	/s/ Richard Ian Griffiths	07 May 2025	0001846370

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	SLN	American Depositary Shares	Purchase		+100,000	+0.93%		10,820,853	05 May 2025	Ordinary Shares	300,000	$3.94	Direct	F1
transaction	SLN	American Depositary Shares	Purchase		+100,000	+0.92%		10,920,850	06 May 2025	Ordinary Shares	300,000	$3.96	Direct	F1
transaction	SLN	American Depositary Shares	Purchase		+50,000	+0.46%		10,970,853	07 May 2025	Ordinary Shares	150,000	$3.81	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.