Richard Ian Griffiths - 31 Mar 2025 Form 4 Insider Report for Silence Therapeutics plc (SLN)

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	SLN	American Depositary Shares	Purchase		+100,000	+1%		9,861,299	31 Mar 2025	Ordinary Shares	300,000	$2.83	By Cream Capital Limited	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Id	Content
F1	Each American Depositary Share ("ADS") is immediately convertible into three ordinary shares for no consideration and has no expiration date.
F2	The securities transactions listed were made by Cream Capital Limited ("Cream"). Mr Griffiths is a director and the controlling shareholder of Cream. Mr Griffiths disclaims beneficial ownership of these securities except to the extent of his proportionate pecuniary interest therein.